Take-Two Interactive recently purchased Irrational Games, who developed the well-known System Shock 2 game. That game was published by Electronic Arts. Take-Two has announced that it will publish Irrational's next game, BioShock, which is touted as the 'spiritual successor"? to System Shock 2 (although it is not a sequel).
Perhaps in related news, EA recently filed a US trade-mark application for SYSTEM SHOCK. Whether this means that a sequel to System Shock 2 is in the works remains to be seen.